|
KMID : 0356920160690040332
|
|
Korean Journal of Anesthesiology
2016 Volume.69 No. 4 p.332 ~ p.340
|
|
|
Surgical site infection after colorectal surgery according to the main anesthetic agent: a retrospective comparison between volatile anesthetics and propofol
|
|
Koo Bon-Wook
Sim Jun-Bo
Shin Hyun-Jung
Kim Duck-Woo
Kang Sung-Bum
Do Sang-Hwan
Na Hyo-Seok
|
|
|
Abstract
|
|
|
Background: Anesthetic agents used for general anesthesia are emerging possible influential factors for surgical site infection (SSI). In this retrospective study, we evaluated the incidence of SSI after colorectal surgery according to the main anesthetic agents: volatile anesthetics vs. propofol.
Methods: A total 1,934 adult patients, who underwent elective colorectal surgery under general anesthesia between January 2011 and December 2013, were surveyed to evaluate the incidence of SSI: 1,519 using volatile anesthetics and 415 using propofol for main anesthetic agents. Patient, surgery, and anesthesia-related factors were investigated from all patients. Propensity-score matching was performed to reduce the risk of confounding and produced 390 patients in each group.
Results: Within the propensity-score matched groups, the incidence of SSI was higher in the volatile group compared with the propofol group (10 [2.6%] vs. 2 [0.5%], OR = 5.0 [95% CI = 1.1-2.8]). C-reactive protein was higher in the volatile group than in the propofol group (8.4 ± 5.6 vs. 7.1 ± 5.3 mg/dl, P = 0.001), and postoperative white blood cells count was higher in the volatile group than in the propofol group (9.2 ± 3.2 × 103/μl vs. 8.6 ± 3.4 × 103/μl, P = 0.041).
Conclusions: The results of this study suggest that intravenous anesthesia may have beneficial effects for reducing SSI in colorectal surgery compared to volatile anesthesia.
|
|
|
KEYWORD
|
|
|
Inhalation anesthesia, Propofol, Surgical site infection
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
   
|
|